Steve Ealick's Research Group

Mariya Morar

Email: mm424@cornell.edu

BS: Chemistry/Biochemistry, University of West Florida, 2003

Experience:

Sixth year graduate student in Chemistry.

Current Project:

Structure of enzymes involved in the purine biosynthetic pathway and in the synthesis of aromatic amino acids.

Publication:

Morar M, Anand R, Hoskins AA, Stubbe J and Ealick SE. Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP-binding Protein Superfamily. Biochemistry 45:14880-14895 (2006). PubMed. Abstract.

Hoskins AA, Morar M, Kappock TJ, Mathews II, Zaugg JB, Barder TE, Peng P, Okamoto A, Ealick SE, and Stubbe J. N⁵-CAIR Mutase: the Role of a CO₂ Binding Site and Substrate Movement in Catalysis. Biochemistry 46:2846-2855. Abstract. PubMed.

Morar M, White RH and Ealick SE. Structure of 2-Amino-3,7-dideoxy-D-threo-hept-6-ulosonic Acid Synthase, a Catalyst in a Novel Pathway for the Biosynthesis of Aromatic Amino Acids. Biochemistry. Biochemistry 46:10562-10571(2007). Abstract. PubMed.

Morar M, Hoskins AA, Stubbe J, and Ealick SE. Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima: Structural Insights into Complex Formation. Biochemistry 47:7816-7830 (2008). Abstract. PubMed.

Zhang Y, Morar M and Ealick SE. Structural biology of the purine biosynthetic pathway. Cell. Mol. Life Sci. Accepted. Abstract. PubMed