Steve Ealick's Research Group

Structures



Saccharomyces cerevisiae
MilB

Pyrococcus furiosus Quinolinate Synthase

Clostridium botulinum Thiaminase I
 

Candida albicans THI5p

Pseudouridine Monophosphate Glycosidase


Klebsiella pneumoniae HpxO

Clostridium botulinum
BcmB

Saccharomyces cerevisiae
THI20

Human Spermidine Synthase


Wolinella succinogenes O-Acetylhomoserine Sulfhydrylase


Bacillus cereus Adenosine Phosphorylase

Leishmania donovani
UMPS

Klebsiella pneumoniae HpxA

Klebsiella pneumoniae
5-Hydroxyisourate Hydrolase (HpxT)

Streptococcus pyogenes Uridine Phosphorylase

Bacillus halodurans ThiY


Candida glabrata
THI6

Toxoflavin Lyase

Leishmania donovani
OMPDC



Dph2 from Pyrococcus
horikoshii



HpxJ from Klebsiella pneumoniae


Klebsiella pneumoniae HpxQ

Streptococcus pneumoniae Nicotinamidase

GIV Purine Nucleoside Phosphorylase


E-2-(Acetamidomethylene)succinate Hydrolase


Human Desarg-C5A

Uridine Phosphorlase
Bos taurus

PurLQS
Thermotoga maritima


CysO-CysM Complex
Mycobacterium tuberculosis


HMP-P Synthase (ThiC)
Caulobacter crescentus

MHPC Oxygenase

Methanocaldococcus jannaschii PurP

Pyrococcus furiosus PurP

Thiamin Binding Protein
Escherichia coli

Thiamin Monophosphate Kinase

Aquifex aeolicus


Tryptophan 2,3-dioxygenase (TDO)
Ralstonia metallidurans


Inosine 5'-monophosphate Cyclohydrolase (PurO)
Methanobacterium thermoautotrophicum


ADH Synthase
Methanocaldococcus jannaschii

HMPD Decarboxylase
Mesorhizobium loti MAFF303099

Methylthioadenosine Phosphorylase II
Sulfolobus solfataricus

Thi4
Saccharomyces cerevisiae

YaaDE
Thermotoga maritima

Formylglycinamide Ribonucleotide Amidotransferase (PurL)
Thermotoga maritima

Purine Nucleoside Phosphorylase
Trichomonas vaginalis

Deoxycytidine Kinase
Human


ThiSF
Escherichia coli

RNAase A

TenA
Bacillus subtilis

TenI
Bacillus subtilis

Uridine Phosphorylase
Salmonella typhimurium

3-Hydroxyanthranilate-3,4-Dioxygenase
Ralstonia metallidurans

PurS
Bacillus subtilis

ThiSG
Bacillus subtilis

Aminoimidizole Riboside Kinase
Salmonella enterica

N5-Carboxyaminoimidazole Ribonucleotide Mutase (PurE)
Acetobacter aceti

Purine 2'-Deoxyribosyltransferase
Lactobacillus helveticus

AMP Nucleosidase
Escherichia coli

S-Adenosylmethionine Decarboxylase
Thermotoga maritima

PurL
Salmonella typhimurium

ThiO
Bacillus subtilis

Phosphopantothenoylcysteine Synthetase
Human

Phosphopantothenoylcysteine Decarboxylase
Human

YaaE
Bacillus subtilis

Hydroxymethylpyrimidinephosphate Kinase (ThiD)
Salmonella typhimurium

Variant 2 Toxin
Centruroides sculpturatus Ewing

S-Adenosylmethionine Decarboxylase
Solanum tuberosum (potato)

Arginine Decarboxylase
Methanococcus jannaschii

ADP-L-Glycero-D-Mannoheptose 6-Epimerase
Escherichia coli

4-Methyl-5-β-Hydroxyethylthiazole Kinase (ThiM)
Bacillus subtilis

Methylthioadenosine Phosphorylase
Sulfolobus solfataricus

Oxalate Decarboxylase
Bacillus subtilis

Aminoimidazole Ribonucleotide Synthetase (PurM)
Escherichia coli

Interferon-γ/Interferon-γ Receptor Complex
Human

Adenosine Kinase
Toxoplasma gondii

Orotidine 5'-Monophosphate Decarboxylase
Bacillus subtilis

N5-CAIR Mutase (PurE)
Escherichia coli

S-Adenosylmethionine Decarboxylase
Human

Thiamin Phosphate Synthase
Bacillus subtilis

5'-Deoxy-5'-Methylthioadenosine Phosphorylase
Human

Purine Nucleoside Phosphorylase
Bovine Spleen

Pyrimidine Nucleoside Phosphorylase
Bacillus stearothermophilus

Glycinamide Ribonucleotide Synthetase (PurD)
Escherichia coli

Thiaminase I
Bacillus thiaminolyticus

Rusticyanin
Thiobacillus ferrooxidans

Purine Nucleoside Phosphorylase
Human

Purine Nucleoside Phosphorylase
Escherichia coli

Adenosine Kinase
Human

Granulocyte Macrophage Colony Stimulating Factor
Human

Interleukin-4
Human

Uridine Phosphorylase
Escherichia coli

Nucleoside 2-Deoxyribosyltransferase
Lactobacillus leichmanii

Thymidine Phosphorylase
Escherichia coli

Sarcoplasmic Calcium-Binding Protein
Nereis diversicolor

Recombinant Human Interferon-γ

Variant 3 Toxin
Centruroides sculpturatus

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